Three Seriously Injured in Highway 50 Crash in Cole County.

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🗓 Published: November 11, 2026 9:03 PM (11 minutes ago)

Three people were following a two-vehicle collision that caused traffic delays on Highway 50 in Cole County on Tuesday afternoon.

The Missouri State Highway Patrol (MSHP) reported that a 2022 Altima was traveling west on Highway 50 at Lookout Trail when a southbound 2015 Tacoma attempted to cross the westbound lanes around 4:15 p.m.

The Nissan struck the left side of the Tacoma, resulting in the crashing into a road sign.

Two women from California, Mo.—a 48-year-old and a 24-year-old—sustained serious injuries and were transported to University Hospital by EMS.

The 68-year-old male driver of the Tacoma from Mokane also suffered serious injuries and was taken to Capitol Region Medical Center for treatment.

According to MSHP, all three individuals were wearing seatbelts at the time of the crash.

Traffic was impacted in the area as investigations continue, with authorities assessing the scene for further details.

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