Two men sustained serious injuries in a crash on Old Highway 54 south of Fulton on Saturday afternoon.
The Missouri State Highway Patrol reported the incident occurred at 4:04 p.m., north of Propertee Drive.
A 1995 Chevrolet Silverado, driven by a 38-year-old man from Fulton, was traveling southbound when it failed to negotiate a curve.
The vehicle crossed the center line, left the road, and subsequently struck a 2014 Ford Focus, also traveling south, driven by a 38-year-old woman from Fulton.
Following the initial impact, the Silverado overturned, resulting in a second collision with the Ford.
Both the driver of the truck and a 39-year-old man from New Bloomfield, a passenger in the Ford, were reported to have serious injuries.
Emergency response agencies were on the scene, and further investigation is underway.